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Familial Periodic Nystagmus, Vertigo, and Ataxia
James C. White, MD, MS
Arch Neurol. 1969;20(3):276-280.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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A FAMILIAL disorder is described in which recurrent attacks of nystagmus, vertigo, and ataxia occur. The clinical picture differs from similar families previously described in that the onset is in early childhood and that the prognosis may be good (Table).
Twenty-three of 62 members (five generations) of a family have been found to be affected with a periodic nystagmus, vertigo, and ataxia with onset in early childhood. One individual developed permanent ataxia in later life, but two underwent abatement of all symptoms by 30 years of age. The remainder continue to experience attacks, often of decreased intensity, throughout adult life. The pattern of inheritance appears to be as a single autosomal dominant trait.
Report of Cases
Patient No. 15 (Figure) is a 31-year-old white man who from early childhood has suffered recurrent attacks of vertigo, nystagmus, and ataxia of varying degrees of severity and duration. On about six of every
. . . [Full Text PDF of this Article]
Author Affiliations
San Jose, Calif
From the Department of Neurology, San Jose Medical Clinic, San Jose, Calif, and the Stanford University College of Medicine.
Footnotes
Submitted for publication July 15, 1968; accepted Sept 16.
Reprint requests to Department of Neurology, San Jose Medical Clinic, San Jose, Calif 95112.
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