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Human Muscle Spindle Histochemistry
Alfred J. Spiro, MD;
Rebecca L. Beilin, BA
Arch Neurol. 1969;20(3):271-275.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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SEVERAL recent histochemical studies of muscle spindles1-9 have demonstrated the relative activity of various enzymes and other components in the different types of intrafusal fibers. With a single exception consisting of a brief report6 these results were based on studies of subhuman species. Since species differences in histochemical reactions of intrafusal fibers have been documented,1,4,6,7 conclusions drawn from nonhuman studies may be misleading when attempts are made to extrapolate these results to human muscle.
The purpose of this report is to describe the histochemistry of the nonnervous portion of normal human muscle spindles and to compare the reactions of intrafusal fibers with those of extrafusal fibers.
Material and Methods
For obvious reasons muscle tissue suitable for histochemical investigation is difficult to obtain from humans with no evidence of muscle disease. Biopsy specimens used in this study were obtained from the patients described below for the reasons listed.
. . . [Full Text PDF of this Article]
Author Affiliations
New York
From the Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY.
Footnotes
Submitted for publication Oct 3, 1968; accepted Nov 8.
Reprint requests to Albert Einstein College of Medicine, Eastchester Rd and Morris Park Ave, Bronx, NY 10461 (Dr. Spiro).
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