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JOHN R. KNOTT, Ph.D.; W. R. INGRAM, Ph.D.; ROBERT E. CORRELL, Ph.D.

AMA Arch Neurol. 1960;2(4):476-484.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The effects of subcortical electrical stimulation on electroencephalographic activity, physiologic reactions, and spontaneous behavior of animals have received considerable attention. In 1949 Moruzzi and Magoun¹³ reported that stimulation of the reticular formation of the brain stem produced a low-voltage fast electroencephalogram, characteristic of the alert state. These effects might be mediated in part by the diffuse projection system of Jasper.⁸ Ingram, Knott, and Chiles⁷ showed that, in the unanesthetized animal, stimulation of the reticular system would evoke behavioral, as well as electrical, alerting.

Hess^4,5 has studied at length the effects of diencephalic stimulation on the spontaneous behavior of the unanesthetized animal and obtained a variety of responses, both autonomic and somatic in nature. Using anesthetized cats, Kaada¹⁰ elicited both autonomic and somatic responses from stimulation of rhinencephalic structures, but failed to evoke any autonomic reactions from stimulation of the hippocampus. MacLean and Delgado¹¹ . . . [Full Text PDF of this Article]

Author Affiliations
Iowa City

Departments of Anatomy and Psychiatry, State University of Iowa School of Medicine.

Present address (Dr. Correll): Neurophysiology Laboratory, Hartford Hospital, Hartford 2, Conn.

Footnotes
Received for publication Aug. 7, 1959.

This study was supported by U. S. Public Health Service, Grant No. M 675 and continuations.

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