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NORMAN C. HILL, M.D.; NORMAN P. GOLDSTEIN, M.D.; BERNARD F. McKENZIE, M.S.; WARREN F. McGUCKIN, Ph.D.; HENDRIK J. SVIEN, M.D.

AMA Arch Neurol. 1960;2(3):341-347.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This investigation was undertaken to determine whether characteristic changes occur in the serum proteins, glycoproteins, and lipoproteins in various neurologic diseases. We hoped to gain information on the pathogenesis of the particular disease under consideration and on the response of the body to it. Furthermore, we hoped such information might be helpful in differential diagnosis.

Many non-neurologic diseases cause changes in serum proteins,¹ glycoproteins,² and lipoproteins³; diseases arising outside the nervous system were excluded from this study.

A number of investigators have reported on changes in serum proteins accompanying multiple sclerosis^4-7; others have studied blood lipids and lipoproteins with particular reference to multiple sclerosis.^8-10 Roboz and co-workers¹¹ recently contributed findings regarding changes in serum polysaccharides in patients with brain tumor.

Material

In this report we are presenting observations on the serum proteins, glycoproteins, and lipoproteins in 135 cases that represent a number of commonly . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn.

Fellow in Neurosurgery, Mayo Foundation (Dr. Hill). Section of Neurology (Dr. Goldstein); Section of Biochemistry (Mr. McKenzie and Dr. McGuckin); Section of Neurologic Surgery (Dr. Svien), Mayo Clinic and Mayo Foundation. The Mayo Foundation, Rochester, Minn., is a part of the Graduate School of the University of Minnesota.

Footnotes
Accepted for publication Oct. 21 1959.

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