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HARTWELL G. THOMPSON, Jr, M.D.; MALCOLM B. CARPENTER, M.D.

AMA Arch Neurol. 1960;2(2):183-187.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although the association of ballism and chorea with localized lesions in the subthalamic nucleus appears well established,^1-3 and experimental studies^4-7 have demonstrated that a similar form of dyskinesia can be produced by lesions in this nucleus in the rhesus monkey, relatively few cases of chorea or ballism due to metastatic lesions of the subthalamic nucleus have been reported. According to Whittier,² ballism most frequently occurs in hypertensive persons as a consequence of localized hemorrhage into the corpus Luysi (subthalamic nucleus). Only two reports^8,9 of ballism due to metastatic neoplasms (both primary in the breast) have been reported; this syndrome also has been reported in association with a discrete tubercle.¹⁰

The current case was considered noteworthy not only because the dyskinesia appeared to be associated with a discrete metastasis but also because the chorea developed slowly, was somewhat intermittent in severity, and was exaggerated by the . . . [Full Text PDF of this Article]

Author Affiliations
New York

Trainee (BT254) of the U.S. Public Health Service, National Institutes of Neurological Diseases and Blindness (Dr. Thompson).

Footnotes
Accepted for publication Oct. 5, 1959.

Aided by a grant (B-1538C) from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Bethesda, Md.

The Medical Service of the Francis Delafield Hospital, and the Departments of Neurology and Anatomy, Columbia University College of Physicians and Surgeons.

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