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SAUL R. KOREY, M.D.

AMA Arch Neurol. 1960;2(2):140-145.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The concept that Schwann and glial cells are related causally to myelin formation evolved slowly, and not without controversy. Perhaps Doinikow¹ and del Rio Hortega² were the chief advocates of the theory that myelin was a product of the activity of Schwann cells in the peripheral nervous system and of oligodendroglia cells within the central nervous system. Debate may still be had when the electron microscopists^3,4 attempt to decide which of the glial cells carries the name oligodendrocyte. However, it would not be anticipating our discussion to say that at present there is general agreement with the thesis of Doinikow and del Rio Hortega.^3-5

The glial cells again are receiving unexpected interest from contemporary experimentalists.^6,7 It has become apparent that there is a spectrum of enzymes and coenzymes present in white matter,^8-12 many of which may be located intraglially. Recent studies¹³ have shown . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Division of Neurology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University.

Footnotes
Accepted for publication Aug. 4, 1959.

This investigation was supported by Grant No. 163-3 from the National Multiple Sclerosis Society and Grant B1006-C4 from the National Institute of Neurological Diseases and Blindness, U.S. Public Health Service.

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