This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (48)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

BARBARA FISH, M.D.

AMA Arch Neurol. 1960;2(2):115-121.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The many physiological disturbances that occur in schizophrenic patients have been recognized since the 19th century. The accumulation of data on hereditary factors in schizophrenia has supported the postulation of a constitutional substrate.¹⁹ However, it is difficult to prove, from the data on adult patients, whether the physiological dysfunctions are the cause of schizophrenia or only the end-result of many years of severe tension or of conditions secondary to hospitalization.²¹ Furthermore, in the adult patient it is difficult to relate the biochemical changes to the clinical symptoms of the disease. The variety, and sometimes contradictory extremes, of the physiological dysfunctions have been explained as a disturbance in the body mechanisms for maintaining physiological equilibrium and homeostasis, particularly when under stress.^14,25 This might produce the lowered threshold for anxiety seen in schizophrenic patients, but it does not explain the complex disorders of thinking, affect, and relationships which are . . . [Full Text PDF of this Article]

Author Affiliations
New York

Associate Professor of Clinical Psychiatry, New York University College of Medicine.

Footnotes
Received for publication May 4, 1959.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?