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I. Epidemiologic Aspects

Kwang-ming Chen, MD; Jacob A. Brody, MD; Leonard T. Kurland, MD

Arch Neurol. 1968;19(6):573-578.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AFTER THE phenomenally high incidence of amyotrophic lateral sclerosis among the Chamorros of Guam was noted, an effort was made to identify other neurologic disorders in the inhabitants of this island.¹1 It soon became evident that the Chamorros also had a high incidence of a form of parkinsonism with dementia² which may be unique to this population. A surveillance program was developed to assess the incidence and prevalence of other neurologic and myopathic disorders and to determine whether any might be associated with amyotrophic lateral sclerosis or parkinsonismdementia. To this end, we analyzed case reports in a fashion similar to that in an earlier epidemiologic study in a population of similar size in Rochester, Minn.³ A second paper will provide a genetic analysis of several familial disorders which have been observed among the Chamorros.

Since 1956 the National Institute of Neurological Diseases and Blindness . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn; Bethesda, Md; Rochester, Minn

From the Mayo Graduate School of Medicine, Rochester, Minn (Dr. Chen); the Epidemiology Branch, National Institute of Neurological Diseases and Blindness, NIH, Bethesda, Md (Dr. Brody); and the Section of Medical Statistics, Epidemiology and Population Genetics, Mayo Clinic, Rochester, Minn (Dr. Kurland).

Footnotes
Submitted for publication June 26, 1968; accepted Aug 29.

Reprint requests to Mayo Clinic, 200 First St, SW Rochester, Minn 55901 (Dr. Kurland).

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