This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (11)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Edgar Maeyens, Jr., BS; Samuel E. Pitner, MD

Arch Neurol. 1968;19(5):538-539.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SERUM creatine phosphokinase (CPK) and aldolase activity usually is elevated in rapidly progressive myopathies, but normal to only slightly above normal in slowly progressive myopathies and neurogenic muscular atrophies.¹ However, both muscle trauma and strenuous exercise can cause transient elevations in serum CPK levels in normal individuals.²

Engel³ recently studied the histologic effects of multiple needle insertions on muscle. He found that apparent "myopathic" changes could be produced in muscle by hypodermic and electromyographic needles. His study suggested the possibility that spurious elevations of serum CPK and aldolase activity also might occur following electromyography (EMG). The purpose of this study was to determine if the minimal muscle trauma associated with EMG could cause significant elevation of serum CPK or aldolase activity.

Materials and Methods

Serum CPK and aldolase levels were determined in 20 consecutive inpatients before and after EMG. There were ten girls and ten . . . [Full Text PDF of this Article]

Author Affiliations
Memphis

From the Department of Neurology, University of Tennessee, and the MDAA-St. Jude Clinic for Neuromuscular Disorders, St. Jude Children's Research Hospital, Memphis.

Footnotes
Submitted for publication July 12, 1968; accepted July 30.

Reprint requests to St. Jude Children's Research Hospital, PO Box 318, Memphis 38112 (Dr. Pitner).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?