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Edwin H. Kolodny, MD; Jean J. Rebeiz, MD; Capt Verne S. Caviness, Jr.; Edward P. Richardson, Jr., MD

Arch Neurol. 1968;19(5):510-524.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AMONG the noninfective inflammatory diseases of the blood vessels is a rare form of granulomatous angiitis that is almost entirely confined to the central nervous system (CNS). The lesions, which are focal and often necrotizing, are generally associated with multinucleate giant cells. Before its delineation as a distinct clinicopathologic entity by Cravioto and Feigin,¹ the condition was variously designated as "Morbus Boeck" (Zollinger²), "allergic angiitis and allergic granulomatosis" (Churg and Strauss,³ Newman and Wolf⁴) and "giantcell arteritis" (McCormick and Neubuerger⁵). To our knowledge, 14 cases of the disorder have been reported up to now,^1,2,4-11 of which two appeared in the form of clinicopathologic discussions in the Cabot case series from the Massachusetts General Hospital.^6,7 These two cases, and two additional ones more recently studied at this hospital, are the subject of the present communication. Serial sections of typical lesions from one of the . . . [Full Text PDF of this Article]

Author Affiliations
USAF (MC) Boston

From the Charles S. Kubik Laboratory for Neuropathology of the James Homer Wright Pathology Laboratories; the Neurology Service, Massachusetts General Hospital; and the departments of neurology (Dr. Kolodny and Capt Caviness), neuropathology (Drs. Rebeiz and Richardson), and pathology, Harvard Medical School, Boston. Dr. Kolodny is now with the National Institute of Neurological Diseases and Blindness, Bethesda, Md; and Dr. Rebeiz is at the American University of Beirut, Lebanon. Dr. Rebeiz is a Rockefeller fellow.

Footnotes
Submitted for publication May 6, 1968; accepted June 7.

Read in part at the 43rd annual meeting of the American Association of Neuropathologists, Atlantic City, NJ, June 10, 1967.

Reprint requests to Charles S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Boston 02114 (Dr. Richardson).

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