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Takehiko Yanagihara, MD; J. N. Cumings, MD

Arch Neurol. 1968;19(3):241-247.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DESPITE various investigations into biochemical aspects relating to cerebral edema surrounding brain tumors in man, such as electrolytes,¹ proteins,² and enzyme activities,³ the studies of lipid metabolism in this pathologic process have been very few,^4,5 and one of them was in an acute pyogenic process.⁵ In each example evidence of demyelination was present. Morphologic investigation using the electron microscope in similar pathologic processes, both in human materials⁶ and in experimental animals, (T. Yanagihara, unpublished data) demonstrated some disturbance in lamination of myelin sheaths. For this reason we have attempted a systematic survey of lipid alterations in relation to the cerebral edema associated with human brain tumors.

Report of Cases

Materials used in this investigation were obtained at autopsy. Short summaries of each clinical history are as follows:

CASE 1.—A 64-year-old male patient was hospitalized with a five-month history of temporal lobe epilepsy . . . [Full Text PDF of this Article]

Author Affiliations
London

From the Department of Chemical Pathology, Institute of Neurology, National Hospital, Queen Square, London.

Footnotes
Submitted for publication March 7, 1968; accepted March 25.

Reprint requests to Institute of Neurology, National Hospital, Queen Sq, London, W.C.1 (Dr. Cumings).

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