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II. An Ultrastructural Study

Claude G. Wasterlain, MD; Richard M. Torack, MD

Arch Neurol. 1968;19(1):79-87.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PREVIOUS morphological studies of cerebral edema in water intoxication have been concerned exclusively when gray matter,^1-5 although it has been well established that the greatest chemical swelling occurs in white matter.⁶ Most observers have found an increase in water content of the brain^6-10 and swelling of glial cells^1,7 in water intoxication, but Gerschenfeld et al have claimed that no chemical or morphological change occurs in the brain in the presence of severe water intoxication.⁷ In view of this controversy, and because of the often-noted differences in the behavior of white and gray matter in other types of brain swelling,^11-16 we undertook this morphological study of white matter edema in water intoxication. It was hoped that such a work, in addition to complementing our chemical data on water intoxication,¹⁷ might provide useful information regarding fluid pathways in the brain.

Material and Methods

Thirty . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the departments of neurology and pathology, Division of Neuropathology, New York Hospital-Cornell Medical Center, New York. Dr. Torack is now at the Department of Pathology, Washington University School of Medicine, St. Louis.

Footnotes
Submitted for publication Oct 24, 1967; accepted Jan 17, 1968.

Reprint requests to 4550 Scott Ave, St. Louis 63110 (Dr. Torack).

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