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Shukuro Araki, MD; Shiro Mawatari, MD; Michiya Ohta, MD; Akira Nakajima, MD; Yoshigoro Kuroiwa, MD

Arch Neurol. 1968;18(6):593-602.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AMYLOIDOSIS, a rare disease of unknown etiology, is characterized by deposition of amorphous hyaline-like material in connective tissues and by slow involvement of various organs. The clinical manifestations depend upon the rapidity of the involvements and the location of the lesions. The primary type of amyloidosis affects mainly tissues of mesodermal origin, especially the heart, tongue, lungs, striated muscle, gastrointestinal tract, and blood vessels; death is usually due to the cardiac changes.

Nervous system involvement in sporadic cases of primary amyloidosis has been reported by several authors who found that the peripheral nerve deposits were prominent, but brain and spinal cord were usually unaffected.^1,2

In 1950 Ostertag³ first reported a familial form of primary amyloidosis. Subsequently there were several reports of similar families^4-8 in which peripheral neuropathy occurred in 93% of the cases reported. In contrast, neuropathy is uncommon in sporadic cases.⁷

In Japan, reports . . . [Full Text PDF of this Article]

Author Affiliations
Fukuoka City, Japan

From the Department of Neurology, Neurological Institute, Faculty of Medicine, Kyushu University, Fukuoka City Japan. Dr. Nakajima is at the Arao City Hospital.

Footnotes
Submitted for publication Oct 17, 1967; accepted Nov 6, 1967.

Reprint requests to Department of Neurology, Neurological Institute, Faculty of Medicine, Kyushu University, Fukuoka City, Japan (Dr. Araki).

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