This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Caused by an Agent Recovered From Burkitt's Lymphoma

J. R. M. Innes, Sc D, PhD, MRCVS, FC Path; Sarah E. Stewart, PhD, MD, LLD; John Landon, PhD, MS

Arch Neurol. 1968;18(5):563-566.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE FOLLOWING data concern unpublished work done in 1965. We have been stimulated to document now our observations as they provide further evidence (Stewart et al, 1967¹) that support the belief that the herpes-type virus of the cultured Burkitt's tumor cells (Epstein et al, 1964, and 1965^2,3 and Stewart et al, 1965^4,5) has biological activity.

The data concerning our agent are given below. In brief, after intracerebral inoculation into Macaca mulatta babies there resulted a devastating malacic and liquefying panencephalitis which is indistinguishable from human herpetic encephalitis. The observation raised many issues.

Necrotizing encephalitis caused by herpes simplex virus in human beings, particularly in babies, is well known (see Pette, 1958⁶ and Blackwood et al 1963⁷). Because of descriptive detail, and because of the great similarity of the lesions to those in our monkeys, reference is necessary to Young et al, 1965⁸ who . . . [Full Text PDF of this Article]

Author Affiliations
Falls Church, Va

From the Bionetics Research Laboratories, Falls Church, Va, and the National Cancer Institute, National Institutes of Health, Bethesda, Md.

Footnotes
Submitted for publication Oct 4, 1967; accepted Nov 13, 1967.

Reprint requests to Bionetics Research Laboratories, Inc., PO Box 26, Falls Church, Va 22046 (Dr. Innes).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?