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By Hugh Davson, DSc. Price, $22. Pp 456. Little, Brown & Co., 34 Beacon, St, Boston, 1967.

Robert A. Fishman, MD, Reviewer

Arch Neurol. 1968;18(4):459-460.

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The substantial advances that have been made in the last decade in our understanding of the physiology of the cerebrospinal fluid are evidenced by this monograph, which will replace Davson's 1956 volume as the standard reference on the subject. Unlike his earlier volume, this entirely new work excludes consideration of the ocular fluids.

The book provides a concise summary of the new morphology of the brain, choroid plexus, and meninges as now understood with electron microscopy and histochemistry. An historical review of the development of the concepts of the blood-brain and cere-brospinal fluid (CSF) barriers is included, as well as a brief summary of current concepts of membrane transport. He emphasizes the contributions of the technique of ventriculocisternal perfusion, developed by Leusen, Pappenheimer, and others, to our understanding of the composition of CSF. The evidence which permits us to identify the composition of CSF with that of the brain's extracellular fluid is given. The constancy . . . [Full Text PDF of this Article]

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