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A Complication of Chronic Hemodialysis

Raul I. Lopez, MD; George H. Collins, MD

Arch Neurol. 1968;18(3):248-259.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

FUNCTIONAL derangement of neurological function as a complication of renal failure is a well-known, though incompletely understood, occurrence.^1-3 With the exception of peripheral neuropathy,⁴ structural lesions of the nervous system of a specific nature have been observed infrequently.³ More recently, however, in association with the newer methods of therapy for chronic renal disease, a variety of neurological complications have arisen, some of which are associated with morphologic changes within the central nervous system. Included among these are the infections which arise presumably as a result of immunosuppressive therapy,^5-7 and degenerations which may be related to nutritional deficiency.^7,8

The occurrence of central pontine myelinolysis in patients of this type has been interpreted by some as the result of a nutritional deficiency.⁸ Although opinion concerning the etiologic basis for central pontine myelinolysis is divided,^9-13 there is a substantial body of evidence to suggest a . . . [Full Text PDF of this Article]

Author Affiliations
Gainesville, Fla

From the departments of neurology (Dr. Lopez) and pathology (Dr. Collins), College of Medicine, University of Florida, Gainesville, Fla.

Footnotes
Submitted for publication Aug 7, 1967; accepted Sept 25.

Reprint requests to Department of Pathology, College of Medicine, University of Florida, Gainesville, Fla 32601 (Dr. Collins).

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