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Sarah A. Luse, MD; William G. Wood, MD

Arch Neurol. 1967;17(3):304-312.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CARBON tetrachloride, one of the currently used lethal solvents, is notorious for its renal and hepatic toxicity. However, little attention has been given to its equally severe effects on the central nervous system (CNS). Stevens and Forster¹ and Cohen² have pointed out that among the earliest as well as most severe aftermaths of carbon tetrachloride poisoning are derangements of the nervous system, including headache, ataxia, vertigo, blurred vision, lethargy, coma, convulsions, optic neuritis, and polyneuritis. The similarity of carbon tetrachloride to chloroform explains its ability to produce narcosis, although severe medullary depression alone would inhibit its use even without the well known renal and hepatic toxicity.

The increased hazards of poisoning when carbon tetrachloride is used in a closed space or in conjunction with alcohol have been well publicized as have the resultant acute renal and hepatic failure. The paucity of reports on nervous system involvement . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the departments of anatomy and pathology, and the Beaumont-May Institute of Neurology, Washington University School of Medicine, St. Louis. The present address of Dr. Luse is Department of Anatomy, College of Physicians and Surgeons, New York.

Footnotes
Submitted for publication March 13, 1967; accepted April 13.

Reprint requests to Department of Anatomy, College of Physicians and Surgeons, Columbia University, New York 10032 (Dr. Luse).

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