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The "Luxury Perfusion Syndrome" of Brain Tissue

K. Høedt-Rasmussen, MD; E. Skinhoj, MD; O. Paulson, MD; J. Ewald, MD; J. K. Bjerrum, MD; A. Fahrenkrug, MD; N. A. Lassen, MD

Arch Neurol. 1967;17(3):271-281.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THIS paper describes the result of simultaneous measurement of the blood flow in 16 regions of the brain using the xenon 133 (¹³³Xe) injection method^1-3 in acute apoplexy. The study demonstrates the existence of hyperemia in some regions in certain cases of this disease. It further demonstrates that the local hyperemia correlated with the angiographic finding of early filling veins, a correlation also noted by Cronquist and Laroche.⁴ Of perhaps greater importance for the understanding of the pathophysiology of apoplexy are our finding of a local loss of the normal regulation to variations of arterial blood pressure and arterial carbon dioxide tension. All these abnormalities are considered to be a consequence of localized tissue acidosis and to constitute an example of the "luxury perfusion syndrome" of brain tissue recently discussed by Lassen.⁵

Methods

Regional cerebral blood flow was studied by the¹³³Xe residue detection method . . . [Full Text PDF of this Article]

Author Affiliations
Copenhagen

From the departments of clinical physiology, neuroradiology, and neuromedicine, and Medical Department B, Bispebjerg Hospital, Copenhagen.

Footnotes
Submitted for publication Feb 18, 1967; accepted April 13.

Reprint requests to Department of Clinical Physiology, Bispebjerg Hospital, Copenhagen (Dr. Lassen).

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