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Thomas E. Henson, MD; Jans Muller, MD; William E. DeMyer, MD

Arch Neurol. 1967;17(3):238-247.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HEREDITARY occurrence of various myopathies is well established.^1-3 Duchenne, in the 1860's, observed a preponderance of affected males, 11 out of 13 cases,⁴ and the eponym "Duchenne muscular dystrophy" has come to epitomize a disease limited to young boys.^4,5 However, familial cases, similar to this type of muscular dystrophy, have also been seen in girls,^6-11 and some 40 cases¹² are known.

The mode of inheritance of muscular dystrophy of later onset is not as clear. Although families with sex-linked inheritance are known,^3,13,14 simple autosomal recessive inheritance usually prevails. There are also many sporadic cases.^12,15

Though a slight preponderance of females has been reported¹⁶ in facioscapulohumeral dystrophy, exclusive involvement of females in one kindred has not been recorded. A family with limb-girdle dystrophy exhibiting precisely such a pattern of inheritance is here presented.

Report of Cases

The following Anglo-Saxon family, residing in . . . [Full Text PDF of this Article]

Author Affiliations
Indianapolis

From the Department of Neurology and the Division of Neuropathology, Indiana University Medical Center, Indianapolis.

Footnotes
Submitted for publication March 20, 1967; accepted April 14.

Reprint requests to Epidemiology Branch, Collaborative and Field Research, National Institute of Neurologic Diseases and Blindness, Bethesda, Md 20014 (Dr. Henson).

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