 |
|
Electromyographic and Histopathologic Correlations in Arthrogryposis
Lawrence D. Amick, MD;
Warren W. Johnson, MD;
Harris L. Smith, MD
Arch Neurol. 1967;16(5):512-523.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
PREVIOUS interpretations of the pathologic processes underlying arthrogryposis multiplex congenita (AMC) have varied markedly. Recently, Smith et al1 have concluded from electromyographic (EMG) observations in 14 patients and Drachman and Banker2,3 have reported from necropsy studies that the underlying process was neurogenic. Adams et al4 reported both neurogenic and myopathic cases confirmed by necropsy. There were decreased numbers of anterior horn cells in the spinal cord of cases considered to be neurogenic. Skeletal muscles showed small myofibers. In myopathic cases there were no spinal cord changes, but diffuse myopathic changes were present in muscle. Banker et al5 reported the autopsy findings in a case of congenital muscular dystrophy, and Pearson and Fowler6 described a necropsy of hereditary nonprogressive muscular dystrophy as causes of arthrogryposis. Bargeton et al7 found changes indicating a collagen disease in their autopsied patient, and in ther opinon the collagen
. . . [Full Text PDF of this Article]
Author Affiliations
Memphis
From St. Jude Children's Research Hospital and the University of Tennessee College of Medicine, Memphis.
Footnotes
Submitted for publication June 17, 1966; accepted Nov 22.
Reprint requests to Department of Neurology, University Hospital, University of Iowa, Iowa City 52241 (Dr. Amick).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
