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I. Functional Studies

Douglas M. Enoch, MD; Frederick W. L. Kerr, MD

Arch Neurol. 1967;16(3):290-306.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE REGULATION of vasopressor and vesicopressor functions by the central nervous system (CNS) occurs at a series of levels, of which the highest are the hypothalamus and the cerebral cortex. Neither of these structures is indispensable for the maintenance of blood pressure, as evidenced by the normal levels that are present after decerebration at the midcollicular level. However, stimulation of the cortex, and particularly the hypothalamus, can produce marked variations in blood pressure which range from increases up to double the resting systolic pressure to decreases of 20 mm Hg or more.

Numerous investigations of the hypothalamic visceromotor pathways followed the initial studies of Karplus and Kreidl.^1-4 A survey of this voluminous literature reveals areas of general agreement and others of controversy.^5-15 It is generally agreed that the most caudal part of the hypothalamus, the periaqueductal gray substance, and the midbrain tegmentum contain areas

Kabat and associates¹² . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn

From the Mayo Clinic and Mayo Foundation. Sections of Neurologic Surgery and Neuroanatomy (Dr. Kerr); and Mayo Graduate School of Medicine, University of Minnesota (Dr. Enoch), Rochester.

Footnotes
Submitted for publication July 30, 1966; accepted Oct 14.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, Minn 55901 (Dr. Kerr).

*The boundaries between the medial and lateral hypothalamic areas are arbitrary. In the present studies a sagittal plane tangential to the lateral surface of the columns of the fornix and lateral surface of the mamillothalamic tract was used as the arbitrary boundary.

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