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H. SCHAUMBURG, MD; R. BYCK, MD; R. HERMAN, MD; C. ROSENGART, MD

Arch Neurol. 1967;16(1):103-109.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WE HAVE studied the histological and clinical effects of low temperatures on the sciatic nerve of the cat. A selective effect on small nerve fibers by chemicophysical means has been previously reported by several workers.^1,2 The possibility that cold might selectively destroy large nerve fibers was suggested by the pathological study of colddamaged nerve by Denny-Brown et al.³ In addition, physiological studies during cooling of peripheral nerve by Douglas and Malcolm⁴ showed selective blockage of small fibers.

Interest in nerve damage by cold received considerable stimulus during the 1940's as a result of exposure injuries consequent to the war. Blackwood⁵ reported findings in 14 cases of immersion foot, mostly in sailors exposed in open boats. He found that immersion for short duration produced less degeneration of axons and myelin than did more prolonged exposures. Blackwood and Russell⁶ produced degeneration in rat nerves by immersing . . . [Full Text PDF of this Article]

Author Affiliations
From the Saul R. Korey Department of Neurology (Dr. Schaumburg and Dr. Rosengart), Department of Pharmacology (Dr. Byck), and the Department of Rehabilitation Medicine (Dr. Byck and Dr. Herman), New York.

Footnotes
Submitted for publication July 15, 1966; accepted Aug 12.

Reprint requests to Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461 (Dr. Schaumburg).

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