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Electron Microscopic Studies

FREDERICK W. L. KERR, MD; ROSS H. MILLER, MD

Arch Neurol. 1966;15(3):308-319.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

LIGHT microscopy of the trigeminal ganglion and posterior root obtained at operation from patients with trigeminal neuralgia has yielded controversial and uncertain results in the past; a review of the literature indicates that the opinions ranged from statements that there were no pathologic changes to those that claimed that there were degenerative changes in myelinated fibers, loss of ganglion cells, pronounced hypertrophy of interstitial tissue, or arteriosclerotic changes.^1-9 The electron microscopic characteristics of the trigeminal ganglion and associated root have been well described;^10-13 until the recent report by Beaver and associates,¹⁴ no investigation of the ultrastructure of the trigeminal nerve in tic douloureux was available. We fully confirm their finding of pathologic changes in myelinated fibers and note some additional changes.

Material and Methods Patients.—

Specimens of the ganglion and posterior root were obtained at operation from 13 patients who had trigeminal neuralgia. Of these, six fulfilled . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN

From Section of Neurologic Surgery, the Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Submitted for publication March 4, 1966; accepted April 14.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, Minn 55901.

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