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Anatomical Confirmation

ALEXANDER T. ROSS, MD; WILLIAM E. DeMYER, MD

Arch Neurol. 1966;15(2):203-205.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE DIAGRAM makers have provided two schemes for the connections through the medial longitudinal fasciculus (MLF) to explain the MLF syndrome in man. Some authorities depict a wiring diagram with internuclear axons running ipsilaterally in the MLF from the 6th to the 3rd nerve nucleus,¹ while other authorities depict a decussation at the 6th nerve level to run in the contralateral MLF.² In the macaque monkey the problem has been resolved.^3,4 The internuclear MLF fibers decussate at the 6th nerve level to run contralaterally. Thus, unilateral MLF lesions cause ipsilateral paralysis of the adducting eye and contralateral horizontal nystagmus in the abducting eye. The situation in man has been obscure because of the lack of suitable clinicopathologic material. In the few anatomically studied cases the clinical picture was beclouded by multiple signs, and the anatomic correlation was beclouded by multiple or extensive lesions.^5-7 The present . . . [Full Text PDF of this Article]

Author Affiliations
INDIANAPOLIS

From the Department of Neurology, Indiana University Medical Center, Indianapolis.

Footnotes
Submitted for publication March 26, 1966; accepted April 22.

Reprint requests to Indiana University Medical Center, 1100 W Michigan St, Indianapolis 46207 (Dr. Ross).

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