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WILLIAM I. ROSENBLUM, MD; HYMAN DONNENFELD, MD; FERNANDO ALEU, MD

Arch Neurol. 1966;14(6):631-643.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PURPOSE of this report is to describe the effects of acute and chronic elevations of blood pressure upon the diameter and reactivity of pial blood vessels, and to describe the presence of cerebral edema in chronic hypertension, a finding that may be related to alterations of vascular permeability. It is necessary to describe and to discuss sequentially the effects of both acute and chronic elevations in blood pressure because observations made in the acute situation have been considered useful in interpreting phenomena seen in the chronic state.^1-3 Other studies, similar in part to this one, have been carried out by Fog,^4-6 Forbes et al,⁷ Byrom,¹ and Meyer et al^2,3; however, the present communication differs in several respects from previous reports. When the effects of acute elevations are considered, only the papers of Fog^4-6 systematically describe the variable alterations in diameter that follow the . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Pathology and the Department of Neurology and Psychiatry, New York University School of Medicine, New York.

Footnotes
Submitted for publication Dec 27, 1965; accepted Jan 15. 1966.

Reprint requests to Laboratory of Experimental Neuropathology, National Institute of Neurological Diseases and Blindness, Bethesda, Md (Dr. Rosenblum).

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