This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (104)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Interaction of Bilateral Cortical Foci in the Intact, the Bilateral Cortical-Callosal, and Adiencephalic Preparation

ELLIOTT M. MARCUS, MD; C. WESLEY WATSON, MD

Arch Neurol. 1966;14(6):601-610.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PRECISE and constant location of origin of the bilateral, symmetrical patterns of electrical discharge as they occur in man with "idiopathic" or "essential epilepsy" ("petit mal" and "grand mal") has not yet been completely defined. The characteristic electroencephalographic patterns which accompany the "absence" seizure of petit mal have not yet been exactly reproduced in animals.

The most distinctive electroencephalographic pattern of idiopathic epilepsy in childhood is the 2.5 to 3.5 cycle-per-second (cps) spike wave associated with the "absence" seizure. This discharge is abrupt in onset, bilateral, nearly synchronous, and of nearly equal amplitude in the two hemisphere. It is often precipitated by hyperventilation and photic stimulation.

Two distinct categories of hypotheses of the location of the lesion responsible for originating the bilateral grouped discharges of idiopathic epilepsy, especially in petit mal, have emerged: (1) The "centrencephalic" hypothesis of exclusive origin of the process giving rise to the spike . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Department of Neurology, New England Medical Center Hospitals and Tufts University School of Medicine, Boston.

Footnotes
Submitted for publication Dec 9, 1965; accepted Jan 26, 1966.

Read in part before the Boston Society of Psychiatry and Neurology on April 18, 1963. Published in part in Transactions American Neurological Association, 1964.

Reprint requests to Department of Neurology, New England Medical Center Hospitals, 171 Harrison Ave, Boston 02111 (Dr. Marcus).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?