This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (7)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

W. H. ISBISTER, MD; PHILIP F. SCHOFIELD, MB, FRCS; H. BRUCE TORRANCE, MCh, FRCS

Arch Neurol. 1966;14(5):512-521.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

RADIOACTIVE XENON (¹³³Xe) inhalation and clearance techniques for the measurement of cerebral blood flow have been described previously.^1-3 It is the purpose of this paper to present in detail our experiences with such a method and to examine the limitations of the method more fully.

Principle of Method

When the inert gas xenon is mixed with air and breathed, it crosses the pulmonary alveolar membrane and is conveyed by the arterial blood to all parts of the body. The isotope of xenon,¹³³Xe, emits a soft -ray of energy equal to 81 kiloelectron volts; thus, cerebral radioactivity, due to the presence of this isotope, can be measured by external scintillation counting. It has been stated^4,5 that the blood flow in the scalp and the scattered radiation from the chest do not contribute significantly to the radioactivity detected in this way.

It is suggested that cerebral . . . [Full Text PDF of this Article]

Author Affiliations
MANCHESTER, ENGLAND

From a Surgical Unit, Manchester Royal Infirmary, Manchester, England.

Footnotes
Submitted for publication Nov 17, 1965; accepted Dec 6.

Reprint requests to Manchester Royal Infirmary, Oxford Road, Manchester 13, England (Mr. Schofield).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?