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RICHARD M. ARMSTRONG, MD; M. HAROLD FOGELSON, MD; DONALD H. SILBERBERG, MD

Arch Neurol. 1966;14(2):208-212.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE THE REPORTS of Wohlfart et al¹ and Kugelberg and Welander,² there have been a number of case reports^3-10 describing patients with slowly progressive proximal limb weakness of neurogenic Origin. The original descriptions include these features: onset of weakness between the ages of 2 and 17 years, slow progression of weakness with atrophy, fasciculations, hyporeflexia, an autosomal recessive inheritance, electromyographic findings, and histological changes on biopsy consistent with a neuropathic lesion.

This report is about a single Negro family of 64 members. Nineteen have been affected with a slowly progressive neurogenic weakness.

Report of Cases

CASE 1.—III-5 is a 37-year-old man presently employed as a taxicab driver and serving as a minister. Weak since childhood, he was able to work as a construction laborer in early adolescence and lift weights of 100 lb. He served two years in the army medical and quartermaster corps and on . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Department of Neurology, Hospital and School of Medicine, University of Pennsylvania, Philadelphia.

Footnotes
Submitted for publication Sept 17, 1965; accepted Oct 21.

Read in part before the 90th Annual Meeting of the American Neurological Association, June 16, 1965.

Reprint requests to the Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, 19104 (Dr. Armstrong).

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