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A Study of 150 Cases

JOHN F. O'CONNOR, MD; DANIEL M. MUSHER, MD

Arch Neurol. 1966;14(2):157-164.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SYSTEMIC lupus erythematosus (SLE) is a diffuse inflammatory disease of un-known etiology. Because it primarily involves the smaller blood vessels and connective tissue, lesions can be found in virtually all organ systems of the body. Approximately 85% to 90% of the patients are female. While SLE can occur at any age, onset is usually during young adulthood. The disease may terminate in a few weeks or run a remittent course over a period of many years. In general, the prognosis is grave. Steroids have been particularly effective in the amelioration of symptoms. They tend to prolong the lifespan of the patient by controlling some of the more serious complications of an acute exacerbation.

In this study all cases of SLE seen at the Columbia-Presbyterian Medical Center are reviewed in order to evaluate the nature of the mental disorders observed. The findings are considered in the light of some previouslyn published . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Psychiatry, College of Physicians & Surgeons, Vanderbilt Clinic, and Columbia Medical Division, Bellevue Hospital, New York.

Footnotes
Submitted for publication Aug 11, 1965; accepted Oct 20.

Reprint requests to Department of Psychiatry, 722 West 168th St, New York, 10032 (Dr. O'Connor).

The term "Organic Mental Syndrome" as used in this paper can be equated with the term "acute brain syndrome" in the Diagnostic and Statistical Mannal—Mental Disorders, American Psychiatric Association, 1952. This disorder is characterized by impairment of orientation, memory, judgment, and other intellectual functions, and by lability and shallowness of affect. Since these changes generally reverse themselves during the course of SLE, the term "acute," rather than "chronic," is applied.

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