This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (34)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

RAYMOND A. CLASEN, MD; PAULINE M. COOKE, MD; SYLVIA PANDOLFI; GEORGE CARNECKI, MD; GEORGE M. HASS, MD

Arch Neurol. 1965;13(6):584-592.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE EXPERIMENTS to be reported represent a continuation of the work done on cerebral injury in monkeys. Standard injuries were produced by freezing through the intact skull of anesthetized animals. This resulted in an area of hemorrhagic necrosis accompanied within four hours by the development of edema in and around the lesion.¹ Efforts were then made to evaluate forms of therapy designed to alleviate this edema through chemical analyses of the damaged tissue. Our last report dealt with intravenous hypertonic urea six hours after injury.² The present report deals with the effects of steroid therapy 12 hours after injury. The antihistamine was added to the therapeutic regimen because Spector³ found that it was necessary to give salicylates and an antihistamine to reduce the edema associated with experimental pleurisy. Since this might also be the case with cerebral edema, it was decided that the combination would more . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Division of Pathology, Presbyterian-St. Luke's Hospital, Chicago.

Footnotes
Submitted for publication July 24, 1965; accepted Sept 15.

Reprint requests to 1753 W Congress Parkway, Chicago, 111 60612 (Dr. Clasen).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?