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  Vol. 13 No. 5, November 1965 TABLE OF CONTENTS
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Demyelinating Disease Presenting as an Intracranial Mass Lesion

LEON D. PROCKOP, MD; E. RALPH HEINZ, MD

Arch Neurol. 1965;13(5):559-564.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

I. Introduction

IT IS WELL KNOWN that many non-neoplastic disease entities may give symptoms and signs which mimic those of an expanding intracranial lesion. None of our diagnostic procedures, including cerebral angiography, is always definitive in diagnosis of the entities. They include: congenital lesions such as aneurysm,1 and arteriovenous malformation2; focal inflammatory and infectious diseases such as brain abscess3; intracranial hemorrhage, infarct formation or edema formation secondary to cerebrovascular disease4; and trauma.4 Leukoencephalopathy of the hemorrhagic type, one form of demyelinating disease, has been reported to present as an intracranial mass lesion, in which the mass effect is related to hemorrhage.5 It is the purpose of this paper to report a case with demyelinating disease without hemorrhage in which the clinical symptoms and cerebral angiograms were interpreted as indicating an expanding intracranial lesion and led to the presumptive diagnosis of brain tumor. . . . [Full Text PDF of this Article]


Author Affiliations

NEW YORK

From the departments of neurology and radiology, College of Physicians and Surgeons, Columbia University and the New York Neurological Institute, Columbia-Presbyterian Medical Center. Chief Resident in Neurology, Presbyterian Hospital and Assistant in Neurology, College of Physicians and Surgeons, Columbia University (Dr. Prockop), and Special Fellow in Neuroradiology, National Institute of Neurological Diseases and Blindness, National Institutes of Health, BT-973-2. Currently Assistant Professor of Radiology, Emory University Clinic, Atlanta (Dr. Heinz).


Footnotes

Submitted for publication June 21, 1965; accepted July 6.

Reprint requests to 710 W 168th St, New York, NY 10032 (Dr. Prockop).



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