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Locating Brain StructuresExtensions to the Impedance Method
BRYAN W. ROBINSON, MD;
JAMES S. BRYAN, MS;
H. ENGER ROSVOLD, PhD
Arch Neurol. 1965;13(5):477-486.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE PRESENT experiment was undertaken to investigate those extensions to the impedance method of locating brain structures necessary to permit its use safely on humans. In previous reports1-3 it was shown that a wide variety of brain structures can be identified with a roving electrode if the impedance of the tissue surrounding the electrode tip is monitored as the electrode is inserted into and through the brain. Before use on man, several factors relating to the necessarily high requirements of safety and of accuracy required systematic investigation. These factors are given below along with the results of the investigation.
Method
Animals and Tracks.—Data were obtained from 60 electrode tracks in ten Macaca mulatta. Six areas for exploration were selected and were the same for each brain, facilitating comparisons. Of the ten animals, six were anesthetized with 50 mg/kg pentobarbital. The other four were killed with an overdose of
. . . [Full Text PDF of this Article]
Author Affiliations
ATLANTA; BETHESDA, MD
From the Laboratory of Psychology and Section on Technical Development, National Institute of Mental Health, Bethesda.
Footnotes
Submitted for publication June 7, 1965; accepted Aug 2.
Reprint requests to Laboratory of Neurophysiology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Ga 30322 (Dr. Robinson).
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