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SIMEON LOCKE, MD; PAUL I. YAKOVLEV, MD

Arch Neurol. 1965;13(5):471-476.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

EVIDENCE for transcallosal projections of the cingulum to the contralateral striatum has been presented in earlier studies in monkeys.^1,2 A striking demonstration of transcallosal connections of the caudate nucleus was obtained in animals which had undergone hemicerebrectomy 19 to 29 months previously.² Since these reports, confirmation of a crossed cortico-striatal projection has been presented for the cat³ and for the rat, cat, and rabbit.⁴ The observation that many of the contralateral projection fibers arise in the cingulum was first made in monkeys with surgical ablation of anterior cingulate gyrus and extension of the lesion into the knee of the corpus callosum.¹ Collaterals of the cingulum were observed to turn medially and ventrally into the corpus callosum (Fig 1, A), where they formed a dorsal and ventral condensation separated by somewhat lighter-staining bundles of commissural fibers in the core of the corpus . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Department of Neurology and the Research Laboratories of Normal and Pathological Anatomy of the Brain at the Warren Anatomical Museum, Harvard Medical School, and the Neurological Unit, Boston City Hospital.

Footnotes
Submitted for publication July 9, 1965; accepted July 20.

Reprint requests to the Neurological Unit, Boston City Hospital, Boston, Mass (Dr. Locke).

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