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Optic Nerve Manifestations of Sarcoidosis
J. G. BLAIN, MD;
W. RILEY, MD;
J. LOGOTHETIS, MD
Arch Neurol. 1965;13(3):307-309.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE FREQUENCY with which the nervous system is involved by sarcoidosis was first emphasized by Colover in 1948.1 Recent studies disclose that the nervous system may be implicated in up to 16% of all cases of sarcoidosis.2 Ocular involvement is more common, being encountered in about 30% of all cases.3-9 The fundus is involved in about 15% of cases of sarcoidosis6 and of these, in one third of the cases the optic disc is involved.5 Thus about 5% of cases of sarcoidosis will have demonstrable changes of the optic papilla. Patients with funduscopic manifestations of sarcoidosis not uncommonly have clinical evidence of nervous system involvement. Gould and Hauffman found that of 40 patients with abnormalities of the fundus due to sarcoid, one third had central nervous system (CNS) manifestations.7
This paper describes the clinical features in three patients with systemic sarcoidosis who had both
. . . [Full Text PDF of this Article]
Author Affiliations
MINNEAPOLIS
From the Division of Neurology, University of Minnesota Hospitals, Minneapolis. Associate Professor Division of Neurology (Dr. Logothetis), NINDB Fellow in Neurology, University of Minnesota (Drs. Blain and Riley).
Footnotes
Submitted for publication Dec 24, 1965; accepted May 16.
Reprint requests to Division of Neuropathology, Department of Pathology, New York University, Bellevue Medical Center, New York, NY 10016.
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