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Isolated Cat Head Perfusion by Donor Dog
ROY L. SWANK, MD, PhD;
WOLFGANG HISSEN, MD
Arch Neurol. 1965;13(1):93-100.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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IN A preceding study,4 it was shown that a cat head, isolated completely by the method of Hirsch et al,5 continued to have unchanged circulation, and unchanged frequency and amplitude of the electroencephalogram (EEG) for one to two hours when perfused with disc oxygenated dog blood, provided the screen filtration pressure (SFP) of the dog blood was kept normal by filtering it through Pyrex glass wool. With increase in the SFP of the perfused blood, the circulation to the isolated cat head decreased and the EEG became isoelectric.
These experiments raise the question of the mechanism of compatibility of blood from different species of animals and may be of importance in the problem of organ transplantation, In many of the experiments just cited, agglutination of mixed dog and cat blood occurred. Yet after filtration of this blood through Pyrex glass wool, the agglutination either disappeared or decreased sufficiently
. . . [Full Text PDF of this Article]
Author Affiliations
PORTLAND, ORE
From the Division of Neurology, Department of Medicine, University of Oregon Medical School.
Footnotes
Submitted for publication Jan 2, 1965; accepted Jan 22.
Reprint requests to University of Oregon Medical School, Portland. Ore 97201 (Dr. Swank).
Pyrex glass wool, Corning glass works; Dacron polyester staple, Du Pont Chemical.
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