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Studies of Human Motor Axons

ROBERT HODES, PhD; IRWIN GRIBETZ, MD; JOEL A. MOSKOWITZ, MD; IRVING H. WAGMAN, PhD

Arch Neurol. 1965;12(5):510-526.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

TEXTBOOKS of physiology and monographs on axonology state, explicitly or implicitly, that nerve fibers of large diameter (and rapid conduction velocity) are more excitable than smaller ones. This statement is not open to question when applied, for example, to threshold differences between A and C fibers, or even between A- and A axons. The concept of size-determination of excitability appears to have become so generalized, however, that if one fiber is larger than another it is assumed ipso facto to have a lower threshold to electrical stimulation.

In this paper we shall show that this concept is not true in the case of a small bundle of motor axons of homogeneous function, in which the constituent fibers are fairly similar in respect to conduction velocity. We have found thresholds for skeletomotor fibers of the human upper and lower extremities to be lower for fibers of slow conduction velocity . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK; SAN FRANCISCO

Footnotes
Submitted for publication Nov 16, 1964; accepted Jan 20, 1965.

Mount Sinai Hospital, Department of Pediatrics (Drs. Hodes, Gribetz, and Moskowitz); University of California, San Francisco Medical Center, Biomechanics Laboratory (Dr. Wagman).

Reprint requests to 11 E 100th St, New York, NY 10029 (Dr. Hodes).

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