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  Vol. 12 No. 5, May 1965 TABLE OF CONTENTS
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Cyclic Activity In Sleep of Macaca Mulatta

ELLIOT D. WEITZMAN, MD; DANIEL F. KRIPKE, BA; CHARLES POLLAK, BS; JERONIMO DOMINGUEZ, MD

Arch Neurol. 1965;12(5):463-467.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

RECENT observations have demonstrated in adult man a basic physiologic periodicity during sleep of 80-90 minutes,1-3 in the adult cat 20-25 minutes4-6 and in the adult rat 13 minutes.7 These cycles consist of alternation of a high voltage slow wave stage with a low voltage fast frequency cortical electroencephalographic sleep stage, the latter occupying 15%-25% of sleep time. Characteristic alterations in a number of autonomic and somatic motor functions have been found to correlate with the EEG pattern.8,9 In this study observations of the periodic EEG and behavioral sleep patterns of Macaca mulatta are reported.

Method

Five M mulatta monkeys, (5-8 lb) had cortical and subcortical electrodes implanted under anesthesia for chronic recordings. The cortical electrodes (three-eighth inch silver discs) were placed on the dura mater through burr holes in the skull and cemented in place with acrylic central cement. Bipolar stainless steel electrodes . . . [Full Text PDF of this Article]


Author Affiliations

NEW YORK


Footnotes

Submitted for publication Sept 11, 1964; accepted Dec 5, 1964.

The Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx. Career Scientist, New York City (Dr. Weitzman).

Reprint requests to Albert Einstein College of Medicine, Eastchester Rd and Morris Park Ave, Bronx, NY, 10461.



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