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An Auto Immune Disease

JEAN-LOUIS RIEHL, MD; W. JANN BROWN, MD

Arch Neurol. 1965;12(1):92-97.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Takayasu's disease (or arteritis) has been defined as "an idiopathic arteritis involving the arch of the aorta and its major branches." It is predominantly a disease of young women which can give rise, in more than 50% of the cases, to severe neurological manifestations.¹

The peculiar restricted anatomical distribution of the arteritis in Takayasu's disease is a puzzle which has led many investigators to doubt that the illness is a "simple" disorder of autoimmunity. For, if this were the case, one would expect a widespread, more generalized arteritis (rather than the selective involvement of the aortic arch and its branches). For this reason and in the absence of any specific laboratory test, the etiology of Takayasu's disease has remained "idiopathic." A recognition and a better understanding of this disease are important for three reasons: (1) The disease is perhaps more common than is suspected (six cases were diagnosed in . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

Footnotes
Submitted for publication March 14, 1964; accepted Sept 9.

University of California at Los Angeles, departments of medicine (neurology) and pathology (neuropathology), The Center for the Health Sciences.

Assistant Professor of Medicine (Dr. Riehl); Associate Professor of Pathology (Dr. Brown).

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