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Size as a Function of Physical Parameters

GERHARDT von BONIN, MD; W. WATSON ALBERTS, PhD; E. W. WRIGHT, JR.; BERTRAM FEINSTEIN, MD

Arch Neurol. 1965;12(1):25-29.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Radiofrequency (RF) power has long been recognized as a tool useful in production of experimental lesions in brains of animals^* and therapeutic lesions in man. However, attempts to quantitate lesion size in terms of input power, current, voltage, or dial settings related to these parameters have not produced uniform results. Among the several reasons for these difficulties are differences in circulation from brain to brain and in different parts of the same brain, and differences in impedance, as well as the problems inherent in an accurate measurement of the power or current actually supplied to the nervous tissue.

We felt that quantitation in terms of brain temperature at electrode tip, time of maintenance of temperature, and dimensions of electrode would provide the best index of size of the resulting lesion, since these parameters directly describe the effect by which RF current produces tissue damage.

In this study, 54 lesions were . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Institute for the Study of Human Neurophysiology, Mount Zion Hospital and Medical Center, San Francisco, California.

Footnotes
Submitted for publication Aug 17, 1964; accepted Sept 3.

Professor Emeritus of Anatomy, University of Illinois, College of Medicine; Neuroanatomist, Mount Zion Hospital and Medical Center (Dr. von Bonin).

Supported by Public Health Service research career program award No. NB-K3 16,729 from the National Institute of Neurological Diseases and Blindness (Dr. Alberts).

This investigation was supported by Public Health Service research grant NB-03180 from the National Institutes of Health, and by grant R-146-61 from the United Cerebral Palsy Research and Educational Foundation.

References 3-6, 8, 9, 12, 13, 18, 24, 25.

References 1, 2, 7, 10, 11, 14-17, 19-23.

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