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Studies in Cats

PAUL R. DYKEN, MD

Arch Neurol. 1964;11(5):521-528.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Alumina cream applications to brain and spinal cord have been carried out in several species of laboratory animals, being variously used to produce seizures^1,2 and other neurological manifestations.^3,4 The study most relevant to the present one is that of Kennard⁵ who described a chronic sensory hyperirritability in cats produced by the lumbar intrathecal injection of alumina cream. She postulated that abnormal sensations developed at a discrete chronic injury but that spread of symptoms could occur to body parts not involved initially in the pathological process. In this regard, the condition bore a striking similarity to causalgia in man.

Through the use of the stimulus-response techniques of neurophysiology, it is now possible to examine the form and distribution of evoked potentials at several levels of the nervous system. Such potentials can be evoked either by tactile or by nerve stimulation. To search for evoked potential changes subsequent to chronic . . . [Full Text PDF of this Article]

Author Affiliations
ST. LOUIS

Department of Neurology and the Beaumont-May Institute of Neurology, Washington University School of Medicine.

Footnotes
Submitted for publication June 26, 1964; accepted June 30.

Special trainee of National Institute of Neurological Diseases and Blindness (7F11NB1150-01).

Work supported by program project grant NB 04513, National Institutes of Health.

As defined in Webster's New International Dictionary, third edition, ie, a condition in which a disagreeable or painful sensation occurs in response to a normally innocuous stimulus (as touch).

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