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WILLIAM DeMYER, MD; PHILIP T. WHITE, MD

Arch Neurol. 1964;11(5):507-520.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The origins of EEG rhythms, the physiologic and pathophysiologic mechanisms, have never been fully defined. Nevertheless in the quest for certainty, clinicians search for EEG patterns which may be diagnostic of a brain lesion or disease. Our study of the EEG's of ten patients having uncleft prosencephalons disclosed some suggestively diagnostic patterns which may be unique but do simulate other disorders. The uncleft prosencephalons of our patients usually were small relative to the cranial volume, and they were surrounded by pools of cerebrospinal fluid. The prosencephalons had different orientations along the sagittal axis of the cranium. These anatomic factors, their relation to cerebral electrogenesis and to the propagation of electrical potentials, provide interesting problems in EEG-pathoanatomic correlation.

Specification of the Teratisms Studied

The generic terms cyclopia-arhinencephaly¹ or holoprosencephaly² designate a graded series of malformations beginning with cyclopia and merging with the normal face and brain.^1-5 Pathognomonic median . . . [Full Text PDF of this Article]

Author Affiliations
INDIANAPOLIS; PHOENIX, ARIZ

Footnotes
Submitted for publication April 4, 1964; accepted June 25.

Associate Professor of Neurology, Indiana University School of Medicine, Special Fellow, National Institute of Neurological Diseases and Blindness, United States Public Health Service (NB18404) (Dr. DeMyer); Barrow Neurological Institute of St. Joseph's Hospital (Dr. White).

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