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Studies in Monkeys

SIDNEY SCHULMAN, MD

Arch Neurol. 1964;11(5):477-499.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The relevance of the thalamus to intelligent behavior, which is suggested by its cortical connections, and by a few impressive, if isolated instances of selective thalamic disease in man,^1-3 has been difficult to verify experimentally. While it is true that deficits in problem solving have been observed in rats^4-6 and cats^7,8 with thalamic lesions, similar studies with monkeys have yielded negative results. Defective performance in delayed response tests in monkeys with bilateral lesions of the dorsomedial nucleus have been sought for particularly, because of the frontal connections of this nucleus, and the consistent impairment in delayed response which is produced by bilateral frontal lesions. However, Walker⁹ and Peters et al¹⁰ found no impairment in delayed response performance in monkeys with bilateral lesions of the dorsomedial nucleus, and Chow,¹¹ likewise, was unable to induce defects in delayed response by combined lesions in the pulvinar . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Footnotes
Read at the 89th annual meeting of the American Neurological Association, Atlantic City, June 15-17, 1964.

The Division of Neurology of the Department of Medicine, The University of Chicago.

This investigation was supported by PHS research grants M-2130 and M-2744 from the National Institute of Mental Health of the United States Public Health Service, and by the Douglas Smith Foundation for Medical Research at the University of Chicago.

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