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II. Histochemical and Quantitative Studies

DAVID M. DAWSON, MD; FLAVIU C. A. ROMANUL, MD

Arch Neurol. 1964;11(4):369-378.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

From the standpoint of the relative activity of a number of enzymes in individual muscle fibers, the histochemical studies presented in a companion article¹ disclosed the presence of eight types of fibers in the calf muscles of the rat. The various types of fibers formed a continuum which could be arbitrarily divided into three groups. The gastrocnemius and plantaris were found to be composed of fibers of all the eight types. Within the gastrocnemius, the different types of fibers were found to have a definite topographical arrangement, some portions containing a majority of fibers of group I and other portions a predominance of fibers of group II. The soleus consisted entirely of fibers of group III.

One of the aims of the presently reported combined histochemical and quantitative study was to obtain quantitative data on the activity of various enzymes in the three groups of fiber types. For . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Neurological Unit, Boston City Hospital, the Department of Neurology, Harvard Medical School, and the Graduate Department of Biochemistry, Brandeis University, Waltham, Mass.

Footnotes
Submitted for publication June 25; accepted June 30.

This work was supported by a research grant (NB-02603) from the National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Md. Dr. Dawson is the recipient of a training grant (BT-1023) from the same source.

This is publication number 305 of the Graduate Department of Biochemistry, Brandeis University, Waltham, Mass.

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