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RICHARD J. SCHAIN, MD

Arch Neurol. 1964;11(3):330-333.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Studies on electrolyte levels in human cerebrospinal fluid (CSF) have often raised the question as to the influence exerted by plasma electrolytes on corresponding levels found in CSF. It has been concluded that CSF potassium levels are independent of plasma potassium while CSF sodium tends to be correlated with plasma levels.^1-3 CSF calcium^4,5 and magnesium^3,5 levels are independent of plasma levels although a recent study on a group of retarded children has reported a positive correlation between CSF and plasma calcium.³

Conclusions arrived at from clinical data are generally dependent on statistical correlations between plasma and CSF electrolyte levels. Studies involving direct alteration of plasma electrolyte levels in experimental animals have provided some data in accord with these clinical findings.^1,6-9 However, many of these studies report only single determinations of elevated plasma and associated CSF levels, or involve other complicating factors. This paper describes experiments . . . [Full Text PDF of this Article]

Author Affiliations
OMAHA

Footnotes
Submitted for publication June 12, 1964.

With the technical assistance of Kathryn O'Brien BS.

Research Associate Professor of Neurology and Psychiatry.

Mental Retardation Clinical Research Center, Department of Neurology and Psychiatry, Nebraska Psychiatric Institute, University of Nebraska College of Medicine.

This investigation was supported by Public Health research grants NB-04785 from the National Institute of Neurological Diseases and Blindness and HD-00370 from the National Institute of Child Health and Human Development.

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