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Case With Focal Neurologic Manifestations

THOMAS H. KOEZE, MD; GERALD H. KLINGON, MD

Arch Neurol. 1964;11(2):191-197.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

We have recently studied a patient with acquired toxoplasmosis with prominent focal neurological signs. Since there is only one previous report of focal Toxoplasma granuloma in the literature, we believe it worthwhile to submit a detailed report of this patient's clinical manifestations and pathologic findings.

Congenital toxoplasmosis was first described in humans by Janku in 1923.¹ Since his report, the signs and symptoms have come to be widely recognized. The triad of choreoretinitis, seizures, and disseminated cerebral calcification constitute a more or less classical picture.

The first report of a patient with acquired toxoplasmosis was made by Pinkerton and Weinman in 1940.² Since this report, numerous cases have been recorded. In general, it has been noted that the symptoms and signs are extremely varied. Several authors^3,4 have described a rash resembling that of Rocky Mountain spotted fever. Reports of infections in laboratory workers have included the occurrence . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Neuropsychiatric Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center.

Footnotes
Submitted for publication April 1, 1964; accepted May 5.

United States Public Health Service traineeship grant 2B-5064 (c-5), Department of Medicine, Memorial Sloan-Kettering Cancer Center (Dr. Koeze).

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