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The Effect of Limb Exercise and Hypertensive Agents

WILLIAM F. SAMMARTINO, MD; JAMES F. TOOLE, MD

Arch Neurol. 1964;10(6):590-594.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been demonstrated that the direction of blood flow through the vertebral artery can be reversed by stenosing or occluding the subclavian artery proximal to the subclavian-vertebral junction. This was observed first in man as a result of naturally occurring disease¹ and has been produced experimentally in animals.² In man it has been designated brachial-basilar insufficiency³ or the "Subclavian Steal,"⁶ but for animals a more appropriate term would be reversed vertebral artery flow.

In this syndrome blood from the opposite vertebral, the basilar, and probably the external caroticovertebral and segmental vertebrovertebral anastomotic circulations is diverted into one vertebral artery and shunts distally to the limb (Fig 1). This shunt may be asymptomatic but has been observed to be associated with signs and symptoms of cerebral vascular insufficiency and with intermittent claudication of the limb during exercise.

It seemed to us that fluctuations in systemic blood . . . [Full Text PDF of this Article]

Author Affiliations
WINSTON-SALEM, NC

Footnotes
Submitted for publication Jan 1, 1964; accepted Feb 7.

Formerly Resident in Neurology, Bowman Gray School of Medicine; currently Department of Neurosurgery, New England Center Hospital, Boston (Dr. Sammartino). Professor of Neurology and Chairman of Department, Bowman Gray School of Medicine (Dr. Toole).

Supported by United States Public Health Service grants 2B-5206 and HE-07622-02.

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