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KARL EKBOM, MD; RAGNAR HED, MD; LENNART KIRSTEIN, MD; KARL-ERIK ASTROM, MD

Arch Neurol. 1964;10(5):449-458.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

A previously unrecognized muscular syndrome in chronic alcoholism was described in 1962.¹ The syndrome is characterized by aching, tenderness, and edema in the musculature and develops suddenly after periods of high grade alcoholic abuse. Several patients presented renal damage with hyperpotassemia. Pathological examination demonstrated extensive necrosis of muscular fibers in several cases.

The matter of muscular affections in chronic alcoholism evidently has not received its proper attention. We have, therefore, continued to study this problem and examined 14 more persons with a well-documented history of long-standing abuse. Two cases from the previously mentioned work were included for comparison. The study showed that signs of muscular affections were common. The cases can be classed in three groups, as follows:

1. The patients have acute signs and symptoms of the type already referred to.

2. There are no signs of acute disease but weakness of the proximal limb and girdle . . . [Full Text PDF of this Article]

Author Affiliations
STOCKHOLM, SWEDEN

From the Departments of Medicine IV and Clinical Neurophysiology, Södersjukhuset, Stockholm, and the Department of Pathology II, Karolinska Institutet, Stockholm, Sweden.

Footnotes
Submitted for publication Dec 26, 1963; accepted Feb 14, 1964.

This investigation was supported by a grant from the Swedish Medical Research Council.

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