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ALBERT L. RHOTON, JR., MD; ANNA-MARIE CARLSSON, MD; MICHEL M. TER-POGOSSIAN, PhD

Arch Neurol. 1964;10(4):369-375.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Early experience in brain tumor localization at this institution, utilizing diiodofluorescein I¹³¹ and scintillation counter "spot checking," proved this technique suitable only for screening.^1,2 Further progress elsewhere included development of scanning scintillation detectors,³ photographic recording,^4,5 and more suitable scanning agents including radiomercury-labeled chlormerodrin (Neohydrin).⁶ Our present program utilizing the above refinements in equipment and radiomercury-tagged chlormerodrin has proved useful in the localization of intracranial tumors in the majority of cases prior to contrast studies.

The isotope initially used was Hg²⁰³ tagged to chlormerodrin. This compound was introduced in 1959 as an agent for brain scanning by Blau and Bender⁶ who found it significantly better than albumin I^131.7 Hg²⁰³ decays with a half life of 45.8 days with the emission of a low energy β-particle to an excited state of Tl²⁰³, which in turn emits a single 0.28 mev -ray. . . . [Full Text PDF of this Article]

Author Affiliations
ST. LOUIS

From the Division of Neurological Surgery, the Central Clinical Isotope Laboratory and the Mallinckrodt Institute of Radiology, Washington University School of Medicine.

Fellow in Neurological Surgery (Dr. Rhoton); Central Clinical Isotope Laboratory (Dr. Carlsson); Professor of Radiophysics, the Mallinckrodt Institute of Radiology (Dr. Ter-Pogossian).

Footnotes
Submitted for publication Sept 9, 1963; accepted Oct 15.

Aided by a grant from the Allen P. and Josephine B. Green Foundation.

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