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Serum Lipid and Cholesterol Levels in Cerebrovascular Disease
JOHN S. MEYER, M.D.;
ARTHUR G. WALTZ, M.D.;
JOSEPH W. HESS, M.D.;
B. ZAK, Ph.D.
AMA Arch Neurol. 1959;1(3):303-311.
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Vascular disease of the brain is an important cause of death and disability in the United States. Recently it has been estimated that there are 2,000,000 people in the United States who are suffering from this condition.1 As a result, there has been increasing interest in the treatment of circulatory insufficiency resulting from atherosclerosis of the major cerebral vessels, since this is the commest single cause of neurological deficit. At present, therapeutic measures are directed toward maintenance of optimum blood pressure and cardiac output, prevention of embolization, and improvement of the collateral circulation by means of anticoagulant drugs or by surgical reconstruction of atherosclerotic carotid and vertebral arteries.2-10 Prevention or arrest of atherogenesis must await a more complete understanding of its cause.
Numerous studies have been reported of serum lipid and cholesterol levels in patients suffering from atherosclerosis of the coronary arteries and aorta, but we have been
. . . [Full Text PDF of this Article]
Author Affiliations
Detroit
From the Departments of Neurology, Wayne State University College of Medicine and the Receiving Hospital of the City of Detroit.
Footnotes
Received for publication March 3, 1959.
This work was aided by grants from the U. S. Public Health Service, the Receiving Hospital Research Corporation, and Parke, Davis Company.
Miss Phylliss Harrison, fourth-year medical student, performed the 60 separate cholesterol and lipid determinations.
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