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Anticoagulation in Cerebral Venous Sinus ThrombosisAre We Treating Ourselves?
Mohammad Wasay, MD, FRCP, FAAN;
Ayeesha Kamran Kamal, MD, FAHA
Arch Neurol. 2008;65(7):985-987.
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There are a lot of things we know for a fact that simply aren't so.
—Kevin J. McGowan
Cerebral venous sinus thrombosis (CVST) is known for its diverse clinical manifestations and unpredictable outcome. Early autopsy data suggest that it is uniformly fatal. However, the International Study on Cerebral Vein and Dural Sinus Thrombosis data show that 8% of patients with CVST died, mainly due to transtentorial herniation, unilateral focal mass effect, or diffuse edema and multiple parenchymal lesions.1
Independent predictors of death due to CVST include coma, age older than 37 years, deep CVST, right intracerebral hemorrhage and posterior fossa lesion, worsening of previous focal deficits or de novo focal deficits, hemorrhage on admission computed tomography, central nervous system infection, and cancer.1 In this cohort of 624 patients, 57% had modified Rankin scores of 0 at 16 months' follow-up, . . . [Full Text of this Article] AUTHOR INFORMATION
Author Affiliations: Department of Neurology, The Aga Khan University, Karachi, Pakistan.
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